Chronic granulocytic leukemia (CGL) during the course of chronic lymphocytic leukemia (CLL): correlation of blood, marrow, and spleen morphology and cytogenetics.

Second malignancies occur with a greater described CLL. One patient received total frequency in patients with chronic Iymbody radiation treatment for his CLL, while phatic leukemia than in the general poputhe second was not treated. It is apparent lation. Previously, 20 patients having CLL that previous therapy may not necessarily have been reported as developing acute be a prerequisite for the development of a leukemia, but no cases of development of second malignancy in CLL. Cytogenetics chronic granulocytic leukemia have been offers a useful tool to confirm morphologic observed. In the present report, we will criteria in establishing the diagnosis of a describe patients with Ph’ chromosome second neoplasm. positive CGL associated with previously